Difference between revisions of "Citalopram-maprotiline"

From Psychiatrienet
Jump to: navigation, search
(10 intermediate revisions by 5 users not shown)
Line 1: Line 1:
 
{{Drugswitch
 
{{Drugswitch
 
| from = citalopram
 
| from = citalopram
| to = imipramine
+
| to = maprotiline
| stop =  
+
| stop = {{StopCitalopram}}
* Day 0: gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.
 
* Day 1: Reduce dosage of citalopram/escitalopram to a maximum of 10 mg/day resp. 5 mg/day.
 
 
| start =  
 
| start =  
* Day 1: simultaneously start administration of maprotiline in a normal dosage of 25-75 mg/day.
+
* '''Day 8:''' start administration of maprotiline in a normal dosage of 25 mg/day.
* Day 8: stop administration of citalopram/escitalopram and continue administration of maprotiline only.  
+
* '''Day 15:''' increase dosage of maprotiline.  
| info =  
+
| info = *{{theorSS}}
* “Start low, go slow” for maprotiline is not required, but caution is necessary.
 
* The same applies to [[escitalopram]].
 
 
}}
 
}}

Revision as of 13:26, 28 October 2015

Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram
Maprotiline
Type Antidepressant
Group NRI
links
Medscape Maprotiline
PubChem 4011
PubMed Maprotiline
Kompas (Dutch) Maprotiline
Wikipedia Maprotiline

Switch medication from citalopram to maprotiline.[1] [2]

Nietinrijdenbord.png Stop citalopram
  • Before day 1: gradually reduce dosage of citalopram to a maximum of 20 mg/day, when this dosage is > 20 mg/day.
  • Day 1: reduce dosage of citalopram to a maximum of 10 mg/day.
  • Day 8: stop administration of citalopram
Eenrichtingbord.png Start maprotiline
  • Day 8: start administration of maprotiline in a normal dosage of 25 mg/day.
  • Day 15: increase dosage of maprotiline.
Infobord.png More information
  • Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.