Difference between revisions of "Citalopram-trazodone"

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* Citalopram/escitalopram slows the metabolism of trazodone via CYP2D6, so caution is necessary.
 
  
 
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Revision as of 14:42, 4 September 2009

Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram
Trazodone
Type Antidepressant
Group other
links
Medscape Trazodone
PubChem 5533
PubMed Trazodone
Kompas (Dutch) Trazodone
Wikipedia Trazodone

Switch medication from citalopram to trazodone.

Nietinrijdenbord.png Stop citalopram
  • Gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/ day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.
  • When a dosage of 20 mg/day, resp. 10 mg/day, is reached, stop administration.
Eenrichtingbord.png Start trazodone
  • No wash-out period is needed.
  • Start trazodone the next day in a dosage of 10-150 mg/day.
  • If necessary, increase the dosage of trazodone to a maximum of 400 mg/day.
Infobord.png More information
  • Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
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