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Combining-Aripiprazole-Olanzapine

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Aripiprazole
Type Antipsychotic
Group Atypical AP
Other use moodstabilizer
links
Medscape Aripiprazole
EMEA abilify
PubChem 60975
PubMed Aripiprazole
Kompas (Dutch) Aripiprazole
Wikipedia Aripiprazole
Olanzapine
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AH03
Medscape Olanzapine
EMEA zyprexa
PubChem 4585
PubMed Olanzapine
Drugs.com olanzapine
Kompas (Dutch) Olanzapine
Wikipedia Olanzapine

Adding olanzapine to aripiprazole.

Infobord.png General information
  
Aripiprazole
  • Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
  
Olanzapine
  • Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
  
Aripiprazole
  
Olanzapine
Eenrichtingbord.png Start olanzapine
  
Olanzapine
  • The combination of these 2 antipsychotics seems to be irrational from a pharmacotherapeutical point of view.
Nietinrijdenbord.png Stop olanzapine
  
Olanzapine
Letopbord.png Cave
  • Agents with anticholinergic properties may have additive effects when used in combination. [4]


  1. 1.0 1.1 1.2 1.3 KNMP; Informatorium Medicamentorum 2015; Monografie "olanzapine" (Dutch)
  2. Farmacotherapeutisch Kompas; Toxicologie (dutch)
  3. Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics; J Clin Psychiatry 2003;64:663-667
  4. Interactions between aripiprazole and olanzapine on drugs.com
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