Difference between revisions of "Combining-Aripiprazole-Risperidone"

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(Created page with '{{Drugcombi | base = lamotrigine | add = aripiprazole | info = * Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite. * This combination of drugs may have p...')
 
 
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{{Drugcombi
 
{{Drugcombi
| base = lamotrigine
+
| base = risperidone
 
| add = aripiprazole
 
| add = aripiprazole
 
| info =  
 
| info =  
* Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
 
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
 
 
| start =  
 
| start =  
* Start aripiprazole according to the general dosing advice.
+
{{IrrationalCombiAP}}
* {{Drugscominteract|risperidone-with-lamotrigine-233-0-1430-0|risperidone|lamotrigine}}</ref>
+
| cave =
 +
* Agents with anticholinergic properties may have additive effects when used in combination.<ref name="drugscom">
 +
{{Drugscominteract|risperidone-with-aripiprazole-233-0-2019-0|risperidone|aripiprazole}}</ref>
 
}}
 
}}

Latest revision as of 11:03, 25 June 2010

Risperidone
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AX08
Medscape Risperidone
PubChem 5073
PubMed Risperidone
Drugs.com risperidone
Kompas (Dutch) Risperidone
Wikipedia Risperidone
Aripiprazole
Type Antipsychotic
Group Atypical AP
Other use moodstabilizer
links
Medscape Aripiprazole
EMEA abilify
PubChem 60975
PubMed Aripiprazole
Kompas (Dutch) Aripiprazole
Wikipedia Aripiprazole

Adding aripiprazole to risperidone.

Infobord.png General information
  
Risperidone
  • Risperidone is principally metabolized by CYP2D6 to an active metabolite 9-OH-risperidone (paliperidone).
  
Aripiprazole
  • Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
  
Risperidone
  
Aripiprazole
Eenrichtingbord.png Start aripiprazole
  
Aripiprazole
  • The combination of these 2 antipsychotics seems to be irrational from a pharmacotherapeutical point of view.
Nietinrijdenbord.png Stop aripiprazole
  
Aripiprazole
Letopbord.png Cave
  • Agents with anticholinergic properties may have additive effects when used in combination.[4]


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