Difference between revisions of "Combining-Gabapentin-Lithium"

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(Created page with '{{Drugcombi | base = gabapentin | add = lithium | info = * Gabapentine is eliminated unchanged by the kidney for 100%. * Lithium is eliminated by the kidney for about 95%. Chang...')
 
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* Gabapentine is eliminated unchanged by the kidney for 100%.
 
* Gabapentine is eliminated unchanged by the kidney for 100%.
 
* Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.  
 
* Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.  
* This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects. <ref name=”freeman”> {{Pubmed|9433333|Freeman et al. Mood stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry 1998;155:12-21}}</ref>
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* {{CombiBasic}}
 
| start =  
 
| start =  
 
* Start lithium according to the general dosing advice.
 
* Start lithium according to the general dosing advice.

Revision as of 11:58, 21 April 2010

Gabapentin
Type moodstabilizer
Group anticonvulsant
links
ATC-code N03AX12
PubChem 3446
PubMed Gabapentin
Drugs.com gabapentin
Kompas (Dutch) Gabapentin
Wikipedia Gabapentin
Lithium
Type moodstabilizer
Group other
links
ATC-code N05AN01
Medscape Lithium
PubChem 11125
PubMed Lithium
Drugs.com lithium
Kompas (Dutch) Lithium
Wikipedia Lithium

Adding lithium to gabapentin.

Infobord.png General information
  • Gabapentin is eliminated unchanged by the kidney for 100%.
  • Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
  • Gabapentine is eliminated unchanged by the kidney for 100%.
  • Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
  • This combination of drugs may have possible synergistic effects. However, the pharmacokinetic drug interactions will influence the plasma levels. Dose adaptation is recommended for this combination. [2]
Eenrichtingbord.png Start lithium
  • Start lithium according to the general dosing advice.
Letopbord.png Cave
  • Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. [3]


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