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Combining-Lithium-Gabapentin

118 bytes removed, 11:59, 25 June 2010
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| add = gabapentin
| info =
* Lithium is eliminated by The advantages of gabapentin include the kidney for about 95%. Changes lack of interactions with other drugs in the rate cytochrome P450 system and the lack of excretion can cause unwanted effectsprotein binding. * Gabapentine Since there is eliminated unchanged by the kidney for 100%.* This combination little risk of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effectsuse with lithium is likely to be safe. <ref name=”freeman”> {{Pubmed|9433333|Freeman et al. Mood stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry 1998;155:12-21}}</ref>
| start =
* Start gabapentine according to the general dosing advice.
| cave =
* Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. <ref name="drugscom">
{{Drugscominteract|lithium-with-gabapentin-1147-0-1477-0|lithium|gabapentin}}</ref>
}}
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