Difference between revisions of "Combining-Quetiapine-Risperidone"

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* Start risperidone according to the general dosing advice.
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{{IrrationalCombiAP}}
 
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* Quetiapine may have additive adverse cardiovascular effects in combination with other drugs that are known to prolong the QT interval of the electrocardiogram. <ref name="drugscom">
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* Quetiapine may have additive adverse cardiovascular effects in combination with other drugs that are known to prolong the QT interval of the electrocardiogram. <ref name="drugscominteract">
 
{{Drugscominteract|risperidone-with-quetiapine-2019-1305-1979-1274|risperidone|quetiapine}}</ref>   
 
{{Drugscominteract|risperidone-with-quetiapine-2019-1305-1979-1274|risperidone|quetiapine}}</ref>   
 
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Latest revision as of 10:27, 25 June 2010

Quetiapine
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AH04
Medscape Quetiapine
PubChem 5002
PubMed Quetiapine
Drugs.com quetiapine-fumarate
Kompas (Dutch) Quetiapine
Wikipedia Quetiapine
Risperidone
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AX08
Medscape Risperidone
PubChem 5073
PubMed Risperidone
Drugs.com risperidone
Kompas (Dutch) Risperidone
Wikipedia Risperidone

Adding risperidone to quetiapine.

Infobord.png General information
  • Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.
  • Risperidone is principally metabolized by CYP2D6 to an active metabolite 9-OH-risperidone (paliperidone).
Eenrichtingbord.png Start risperidone
  • The combination of these 2 antipsychotics seems to be irrational from a pharmacotherapeutical point of view.
Letopbord.png Cave
  • Quetiapine may have additive adverse cardiovascular effects in combination with other drugs that are known to prolong the QT interval of the electrocardiogram. [7]


  1. 1.0 1.1 1.2 1.3 1.4 KNMP; Informatorium Medicamentorum 2023; Monografie "quetiapine" (Dutch) Cite error: Invalid <ref> tag; name "informatorium" defined multiple times with different content
  2. NVZA; Toxicology.org; Monografie 73 (dutch)
  3. Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics J Clin Psychiatry 2003;64:663-667
  4. Drugs.com quetiapine-fumarate
  5. Woods SW; Chlorpromazine equivalent doses for the newer atypical antipsychotics J Clin Psychiatry 2003;64:663-667
  6. 6.0 6.1 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives
  7. Interactions between risperidone and quetiapine on drugs.com
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