Difference between revisions of "Combining-Risperidone-Ziprasidone"

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* Stop risperidone before starting ziprasidone.
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* The concurrent use of ziprasidone with other medications that can prolong the QT interval is considered contraindicated.<ref> {{Drugscominteract|risperidone-with-ziprasidone-2019-0-2330-0|risperidone|ziprasidone}}</ref>   
 
* The concurrent use of ziprasidone with other medications that can prolong the QT interval is considered contraindicated.<ref> {{Drugscominteract|risperidone-with-ziprasidone-2019-0-2330-0|risperidone|ziprasidone}}</ref>   
 
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Latest revision as of 10:16, 25 June 2010

Risperidone
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AX08
Medscape Risperidone
PubChem 5073
PubMed Risperidone
Drugs.com risperidone
Kompas (Dutch) Risperidone
Wikipedia Risperidone
Ziprasidone
Type Antipsychotic
Group Atypical AP
Other use Moodstabilizer
links
Medscape Ziprasidone
PubChem 60854
PubMed Ziprasidone
Wikipedia Ziprasidone

Adding ziprasidone to risperidone.

Infobord.png General information
  • Risperidone is principally metabolized by CYP2D6 to an active metabolite 9-OH-risperidone (paliperidone).
  • Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
Eenrichtingbord.png Start ziprasidone
  • The combination of these 2 antipsychotics seems to be irrational from a pharmacotherapeutical point of view.
Letopbord.png Cave
  • The concurrent use of ziprasidone with other medications that can prolong the QT interval is considered contraindicated.[4]


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