Difference between revisions of "Combining-Ziprasidone-Aripiprazole"

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| base = aripiprazole
 
| base = aripiprazole
 
| add = ziprasidone
 
| add = ziprasidone
| info =  
+
| info =
* Ziprasidone is metabolized by CYP3A4 and CYP1A2 (minor).
 
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects.
 
 
| start =  
 
| start =  
* Start ziprasidone according to the general dosing advice.
+
{{IrrationalCombiAP}}
 
| cave =  
 
| cave =  
 
* Agents with anticholinergic properties may have additive effects when used in combination.<ref name="drugscom">  
 
* Agents with anticholinergic properties may have additive effects when used in combination.<ref name="drugscom">  
 
{{Drugscominteract|ziprasidone-with-aripiprazole-233-0-2330-0|ziprasidone|aripiprazole}}</ref>
 
{{Drugscominteract|ziprasidone-with-aripiprazole-233-0-2330-0|ziprasidone|aripiprazole}}</ref>
 
}}
 
}}

Latest revision as of 10:31, 25 June 2010

Ariprazole
Type Antipsychotic
Group Atypical AP
Other use moodstabilizer
links
EMEA abilify
PubChem 60975
PubMed Ariprazole
Kompas (Dutch) Ariprazole
Wikipedia Ariprazole
Ziprasidone
Type Antipsychotic
Group Atypical AP
Other use Moodstabilizer
links
Medscape Ziprasidone
PubChem 60854
PubMed Ziprasidone
Wikipedia Ziprasidone

Adding ziprasidone to aripiprazole.

Infobord.png General information
  • Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
  • Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
Eenrichtingbord.png Start ziprasidone
  • The combination of these 2 antipsychotics seems to be irrational from a pharmacotherapeutical point of view.
Letopbord.png Cave
  • Agents with anticholinergic properties may have additive effects when used in combination.[1]


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