Difference between revisions of "Combining-Ziprasidone-Lithium"

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* Ziprasidone is principally metabolized by CYP2D6 to an active metabolite.
 
 
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* Start lithium according to the general dosing advice.
 
* Start lithium according to the general dosing advice.
 
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| cave =  
* The concomitant administration of lithium with neuroleptic agents may increase the risk of extrapyramidal reactions and neurotoxicity.
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* The concomitant administration of lithium with neuroleptic agents may increase the risk of extrapyramidal reactions and neurotoxicity.<ref name="drugscom">
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{{Drugscominteract|ziprasidone-with-lithium-1477-0-2330-0|ziprasidone|lithium}}</ref>
 
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Latest revision as of 14:13, 15 June 2010

Ziprasidone
Type Antipsychotic
Group Atypical AP
Other use Moodstabilizer
links
Medscape Ziprasidone
PubChem 60854
PubMed Ziprasidone
Wikipedia Ziprasidone
Lithium
Type moodstabilizer
Group other
links
ATC-code N05AN01
Medscape Lithium
PubChem 11125
PubMed Lithium
Drugs.com lithium
Kompas (Dutch) Lithium
Wikipedia Lithium

Adding lithium to Ziprasidone.

Infobord.png General information
  • Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
  • Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
Eenrichtingbord.png Start lithium
  • Start lithium according to the general dosing advice.
Letopbord.png Cave
  • The concomitant administration of lithium with neuroleptic agents may increase the risk of extrapyramidal reactions and neurotoxicity.[2]


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