Difference between revisions of "Combining-Ziprasidone-Olanzapine"

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* Start olanzapine according to the general dosing advice.
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* Agents with anticholinergic properties may have additive effects when used in combination. <ref name="drugscom">
 
{{Drugscominteract|ziprazidone-with-olanzapine-2330-0-1744-0|ziprazidone|olanzapine}}</ref>   
 
{{Drugscominteract|ziprazidone-with-olanzapine-2330-0-1744-0|ziprazidone|olanzapine}}</ref>   
 
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Latest revision as of 11:35, 25 June 2010

Ziprasidone
Type Antipsychotic
Group Atypical AP
Other use Moodstabilizer
links
Medscape Ziprasidone
PubChem 60854
PubMed Ziprasidone
Wikipedia Ziprasidone
Olanzapine
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AH03
Medscape Olanzapine
EMEA zyprexa
PubChem 4585
PubMed Olanzapine
Drugs.com olanzapine
Kompas (Dutch) Olanzapine
Wikipedia Olanzapine

Adding olanzapine to ziprasidone.

Infobord.png General information
  
Ziprasidone
  • Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
  
Olanzapine
  • Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
  
Ziprasidone
  
Olanzapine
Eenrichtingbord.png Start olanzapine
  
Olanzapine
  • The combination of these 2 antipsychotics seems to be irrational from a pharmacotherapeutical point of view.
Nietinrijdenbord.png Stop olanzapine
  
Olanzapine
Letopbord.png Cave
  • Agents with anticholinergic properties may have additive effects when used in combination. [4]


  1. 1.0 1.1 1.2 1.3 KNMP; Informatorium Medicamentorum 2015; Monografie "olanzapine" (Dutch)
  2. Farmacotherapeutisch Kompas; Toxicologie (dutch)
  3. Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics; J Clin Psychiatry 2003;64:663-667
  4. Interactions between ziprazidone and olanzapine on drugs.com
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