Difference between revisions of "Duloxetine-fluoxetine"

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| to = fluoxetine
 
| to = fluoxetine
 
| stop =  
 
| stop =  
* Gradually reduce dosage of duloxetine to a maximum of 60 mg/day.
+
{{downDulox}}
* When a dosage of 60 mg/day is reached, stop administration.
 
 
| start =  
 
| start =  
 
* No wash-out period is needed.  
 
* No wash-out period is needed.  
* Start fluoxetine the next day in a normal dosage of 20 mg/day.
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* ''' Day 2: ''' start fluoxetine in a normal dosage of 20 mg/day.
 
| info =
 
| info =
 
* {{theorSS}}
 
* {{theorSS}}
{{review}}
 
 
}}
 
}}

Revision as of 12:18, 4 November 2015

Duloxetine
Type Antidepressant
Group SNRI
links
Medscape Duloxetine
PubChem 60835
PubMed Duloxetine
Kompas (Dutch) Duloxetine
Wikipedia Duloxetine
Fluoxetine
Type Antidepressant
Group SSRI
links
Medscape Fluoxetine
PubChem 3386
PubMed Fluoxetine
Kompas (Dutch) Fluoxetine
Wikipedia Fluoxetine

Switch medication from duloxetine to fluoxetine.[1] [2]

Nietinrijdenbord.png Stop duloxetine
  • Before day 1: gradually reduce dosage of duloxetine to a maximum of 60 mg/day.
  • Day 1: when a dosage of 60 mg/day is reached, stop administration.
Eenrichtingbord.png Start fluoxetine
  • No wash-out period is needed.
  • Day 2: start fluoxetine in a normal dosage of 20 mg/day.
Infobord.png More information
  • Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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