Switch medication from duloxetine to mianserine.
- Before day 1: gradually reduce dosage of duloxetine to a maximum of 60 mg/ day.
- Day 1: reduce a dosage of 60 mg/day to 30 mg/day.
- Day 8: stop administration of duloxetine.
- Day 8: start mianserine in a low dosage of 30 mg/day.
- Day 15: increase mianserine.
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