Difference between revisions of "Duloxetine-sertraline"

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| to = sertraline  
 
| to = sertraline  
 
| stop =  
 
| stop =  
* Gradually reduce dosage of duloxetine to a maximum of 60 mg/day.
+
{{downDulox}}
* When a dosage of 60 mg/day is reached, stop administration.
 
 
| start =  
 
| start =  
 
* No wash-out period is needed.  
 
* No wash-out period is needed.  
* Start sertraline the next day in a normal dosage of 50 mg/day.
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* ''' Day 2: ''' start sertraline in a normal dosage of 50 mg/day.
 
| info =
 
| info =
 
* {{theorSS}}
 
* {{theorSS}}
{{review}}
 
 
}}
 
}}

Revision as of 12:21, 4 November 2015

Duloxetine
Type Antidepressant
Group SNRI
links
Medscape Duloxetine
PubChem 60835
PubMed Duloxetine
Kompas (Dutch) Duloxetine
Wikipedia Duloxetine
Sertraline
Type Antidepressant
Group SSRI
links
Medscape Sertraline
PubChem 68617
PubMed Sertraline
Kompas (Dutch) Sertraline
Wikipedia Sertraline

Switch medication from duloxetine to sertraline.[1] [2]

Nietinrijdenbord.png Stop duloxetine
  • Before day 1: gradually reduce dosage of duloxetine to a maximum of 60 mg/day.
  • Day 1: when a dosage of 60 mg/day is reached, stop administration.
Eenrichtingbord.png Start sertraline
  • No wash-out period is needed.
  • Day 2: start sertraline in a normal dosage of 50 mg/day.
Infobord.png More information
  • Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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