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Escitalopram-tranylcypromine

Escitalopram
Type Antidepressant
Group SSRI
links
Medscape Escitalopram
PubChem 10832572
PubMed Escitalopram
Kompas (Dutch) Escitalopram
Wikipedia Escitalopram
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from escitalopram to tranylcypromine.

Nietinrijdenbord.png Stop escitalopram
  • Decrease with about 25% of original dose every 3 days
  • Stop and wait 14 days for washout
Eenrichtingbord.png Start tranylcypromine
  • Start tranylcypromine in a low dosage of 20 mg/day for one week.
  • After this week the dosage of tranylcypromine can be increased.
Letopbord.png Cave
  • Occurrence of serotonin syndrome is reported when a wash-out period (of two weeks) is not considered.
  • The reduction of the SSRI doses in 7-14 days could cause emotional instability, headache and flu-like symptoms. One could extend this period.
Infobord.png More information
  • A wash-out period of two weeks is necessary.
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