Difference between revisions of "Fluoxetine-vortioxetine"
From Psychiatrienet
| Line 3: | Line 3: | ||
| to = vortioxetine | | to = vortioxetine | ||
| stop = | | stop = | ||
| − | * '''Before day 1:''' | + | * '''Before day 1:''' reduce dosage of fluoxetine to 20 mg/day, when this dosage is > 20 mg/day. |
| − | * '''Day 1:''' | + | * '''Day 1:''' stop administration |
| start = | | start = | ||
| − | * A wash-out period | + | * '''Day 1-21:''' A wash-out period is needed. |
| − | * '''Day | + | * '''Day 22:''' Start vortioxetine in a dosage of 10 mg/day. |
| − | | info = | + | * '''After day 28 :''' If necessary, increase gradually the dosage of vortioxetine. |
| − | * Fluoxetine | + | | info = |
| − | + | * Fluoxetine slows the metabolism of vortioxetine via CYP2D6, so caution is necessary for at least four weeks after stopping fluoxetine. | |
| − | * | + | * {{theorSS} |
}} | }} | ||
Revision as of 15:23, 12 March 2015
{{Drugswitch | from = fluoxetine | to = vortioxetine | stop =
- Before day 1: reduce dosage of fluoxetine to 20 mg/day, when this dosage is > 20 mg/day.
- Day 1: stop administration
| start =
- Day 1-21: A wash-out period is needed.
- Day 22: Start vortioxetine in a dosage of 10 mg/day.
- After day 28 : If necessary, increase gradually the dosage of vortioxetine.
| info =
- Fluoxetine slows the metabolism of vortioxetine via CYP2D6, so caution is necessary for at least four weeks after stopping fluoxetine.
- {{theorSS}
}}
