Difference between revisions of "Fluvoxamine-duloxetine"
From Psychiatrienet
(Created page with '{{Drugswitch | from = fluvoxamine | to = duloxetine | stop = * Gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day. * When a d...') |
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| to = duloxetine | | to = duloxetine | ||
| stop = | | stop = | ||
| − | * | + | * '''Before day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/day. |
| − | * | + | * '''Day 1:''' stop fluvoxamine. |
| − | | start = | + | | start = |
| − | * | + | * '''Day 5:''' start duloxetine 30 mg/day. |
| − | * | + | * '''Day 14:''' increase administration of duloxetine to 60 mg/day. |
| + | | info = | ||
| + | * Fluvoxamine inhibits the metabolism of duloxetine through CYP1A2. | ||
| + | * {{theorSS}} | ||
Revision as of 09:33, 3 August 2009
{{Drugswitch | from = fluvoxamine | to = duloxetine | stop =
- Before day 0: gradually reduce dosage of fluvoxamine to a maximum of 50 mg/day.
- Day 1: stop fluvoxamine.
| start =
- Day 5: start duloxetine 30 mg/day.
- Day 14: increase administration of duloxetine to 60 mg/day.
| info =
- Fluvoxamine inhibits the metabolism of duloxetine through CYP1A2.
- Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
