| to = amitriptyline
| stop =
* '''Day 1-14:'''Gradually decrease the dosage of hypericum. * '''Day 15:''' stop administration of hypericum.{{Stophyp}}
| start =
* '''Day 15-30:''' a wash-out period of at least two weeks is necessary. {{TCAincrease25p3d}} * '''Day 31:''' start amitriptyline 25 mg/day.| caveat info = {{TCAplasmalevelmonitoring}}* Occurrence The ratio of amitriptyline/nortriptyline could change because of the serotonin syndrome CPY2C19 induction. Sum plasmalevels are not likely to change because CYP2D6 is possible without wash-out periodbarely affected.| info{{caveSS}}
{{HypericumInfo}}
}}