Maprotiline-amitriptyline

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Maprotiline
Type Antidepressant
Group NRI
links
Medscape Maprotiline
PubChem 4011
PubMed Maprotiline
Kompas (Dutch) Maprotiline
Wikipedia Maprotiline
Amitriptyline
Type Antidepressant
Group TCA
links
ATC-code N06AA09
Medscape Amitriptyline
PubChem 2160
PubMed Amitriptyline
Kompas (Dutch) Amitriptyline
Wikipedia Amitriptyline

Switch medication from maprotiline to amitriptyline.[1] [2]

Nietinrijdenbord.png Stop maprotiline
  • Gradually reduce dosage of maprotiline to a maximum of 25-75 mg/day.
  • When a dosage of 25-75 mg/day is reached, stop administration.
Eenrichtingbord.png Start amitriptyline
  • No wash-out period is needed.
  • Start administration of amitriptyline the next day in a normal dosage of 50-100 mg/day.
Infobord.png More information
  • This switch is currently being reviewed.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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