Maprotiline-imipramine

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Maprotiline
Type Antidepressant
Group NRI
links
Medscape Maprotiline
PubChem 4011
PubMed Maprotiline
Kompas (Dutch) Maprotiline
Wikipedia Maprotiline
Imipramine
Type Antidepressant
Group TCA
links
Medscape Imipramine
PubChem 3696
PubMed Imipramine
Kompas (Dutch) Imipramine
Wikipedia Imipramine

Switch medication from maprotiline to imipramine.[1] [2]

Nietinrijdenbord.png Stop maprotiline
  • Gradually reduce dosage of maprotiline to a maximum of 25-75 mg/day.
  • When a dosage of 25-75 mg/day is reached, stop administration.
Eenrichtingbord.png Start imipramine
  • No wash-out period is needed.
  • Start administration of imipramine the next day in a normal dosage of 50-100 mg/day.
Infobord.png More information
  • This switch is currently being reviewed.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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