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Moclobemide-agomelatine

Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide
Agomelatine
Type Antidepressant
Group other
links
ATC-code N06AX22
EMEA valdoxan
PubChem 82148
PubMed Agomelatine
Kompas (Dutch) Agomelatine
Wikipedia Agomelatine

Switch medication from moclobemide to agomelatine.

Nietinrijdenbord.png Stop moclobemide
  • Before day 1: gradually reduce dosage of moclobemide to a maximum of 300 mg/day.
  • Day 1: reduce the dosage of moclobemide to 150 mg/day.
  • Day 8: stop administration of moclobemide.
Eenrichtingbord.png Start agomelatine
  • Day 9: start administration of agomelatine in a dosage of 25 mg/day.
  • Day 16: if necessary, increase dosage of agomelatine to 50 mg/day.

[1]

Infobord.png More information
  • Because of short halve life of moclobemide after stopping, the next antidepressant can start next day.
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