Moclobemide-maprotiline

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Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide
Maprotiline
Type Antidepressant
Group NRI
links
Medscape Maprotiline
PubChem 4011
PubMed Maprotiline
Kompas (Dutch) Maprotiline
Wikipedia Maprotiline

Switch medication from moclobemide to maprotiline.

Nietinrijdenbord.png Stop moclobemide
  • Before day 1: gradually reduce dosage of moclobemide to a maximum of 300 mg/day.
  • Day 1: reduce the dosage of moclobemide to 150 mg/day.
  • Day 8: stop administration of moclobemide.
Eenrichtingbord.png Start maprotiline
  • Day 9: start maprotiline in a normal dosage of 25-75 mg/day.
Infobord.png More information
  • “Start low, go slow” is not required, but caution is necessary.
  • Because of short halve life of moclobemide after stopping, the next antidepressant can start next day.
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