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Moclobemide-trazodone

Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide
Trazodone
Type Antidepressant
Group other
links
Medscape Trazodone
PubChem 5533
PubMed Trazodone
Kompas (Dutch) Trazodone
Wikipedia Trazodone

Switch medication from moclobemide to trazodone.

Nietinrijdenbord.png Stop moclobemide
  • Decrease with about 25% of original dose every 3 days
  • Stop and wait for about 24 hour as a washout period
Eenrichtingbord.png Start trazodone
  • Start with the initial dose
Infobord.png More information
  • Because of short halve life of moclobemide after stopping, the next antidepressant can start next day.
  • A wash-out period of is not necessary.
  • Occurrence of the serotonin syndrome is theoretically possilble, so caution is necessary.
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