Nortriptyline-sertraline

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Nortriptyline
Type Antidepressant
Group TCA
links
Medscape Nortriptyline
PubChem 4543
PubMed Nortriptyline
Kompas (Dutch) Nortriptyline
Wikipedia Nortriptyline
Sertraline
Type Antidepressant
Group SSRI
links
Medscape Sertraline
PubChem 68617
PubMed Sertraline
Kompas (Dutch) Sertraline
Wikipedia Sertraline

Switch medication from nortriptyline to sertraline.

Nietinrijdenbord.png Stop nortriptyline
  • Before day 1: gradually reduce dosage of nortriptyline to a maximum of 100 mg/day.
  • Day 1: reduce dosage of nortriptyline to 50 mg/day.
  • Day 3: reduce dosage of nortriptyline to 25 mg/day.
  • Day 8: stop administration of nortriptyline.
Eenrichtingbord.png Start sertraline
  • Day 1: simultaneously start administration of sertraline in a normal dosage of 50 mg/day.
  • Day 8: stop administration of nortriptyline and continue administration of sertraline in a dosage of 50-100 mg/day.
Infobord.png More information
  • Sertraline is a weak inhibitor of CYP2D6, which metabolizes nortriptyline.
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