Difference between revisions of "Quetiapine"

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Line 3: Line 3:
 
| group = Atypical AP
 
| group = Atypical AP
 
| otheruse = mood stabilizer
 
| otheruse = mood stabilizer
 +
| type = Antipsychotic
 +
| CAS = 111974-69-7
 +
| ChemSpiderID = 4827
 +
| ATC = N05AH04
 
| pubchem = 5002
 
| pubchem = 5002
 +
| drugbank = APRD00675
 
| medscape = 4689
 
| medscape = 4689
 +
| drugscom = quetiapine-fumarate
 
| emea =  
 
| emea =  
 
| ftk = quetiapine
 
| ftk = quetiapine
| type = Antipsychotic
 
 
| metabolization =  
 
| metabolization =  
 
* Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.
 
* Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.
 
| <includeonly> isswitch = 1 </includeonly>
 
| <includeonly> isswitch = 1 </includeonly>
}}
+
| equivalent = 0.03
 +
| equivalent_ref = <ref>Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics ''J Clin Psychiatry'' 2003;'''64''':663-667</ref>
 +
| comparison = haloperidol
 +
| avail = 100
 +
| avail_ref = <ref name="drugscom">{{DRUGSCOM|quetiapine-fumarate}}</ref>
 +
| halflife = 7
 +
| halflife_ref = <ref name="informatorium">{{KNMP|quetiapine}}</ref>
 +
| ct = 4
 +
| ct_ref = <ref name="informatorium" />
 +
| administration = oral
 +
| dose = 25-400
 +
| dose_ref = <ref name="informatorium" />
 +
| DDD = -
 +
| ctox = 500
 +
| ctox_ref = <ref>{{Toxicology|73}}</ref>

Revision as of 19:30, 21 April 2010

{{Drug | name = Quetiapine | group = Atypical AP | otheruse = mood stabilizer | type = Antipsychotic | CAS = 111974-69-7 | ChemSpiderID = 4827 | ATC = N05AH04 | pubchem = 5002 | drugbank = APRD00675 | medscape = 4689 | drugscom = quetiapine-fumarate | emea = | ftk = quetiapine | metabolization =

  • Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.

| | equivalent = 0.03 | equivalent_ref = [1] | comparison = haloperidol | avail = 100 | avail_ref = [2] | halflife = 7 | halflife_ref = [3] | ct = 4 | ct_ref = [3] | administration = oral | dose = 25-400 | dose_ref = [3] | DDD = - | ctox = 500

| ctox_ref = [4]

  1. Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics J Clin Psychiatry 2003;64:663-667
  2. Drugs.com quetiapine-fumarate
  3. 3.0 3.1 3.2 KNMP; Informatorium Medicamentorum 2023; Monografie "quetiapine" (Dutch)
  4. NVZA; Toxicology.org; Monografie 73 (dutch)