Risperidone LA-Fluphenazine LA

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Risperidone
long acting
Type Antipsychotic
Group Atypical AP
links
Medscape Risperidone
PubChem 5073
PubMed Risperidone
Kompas (Dutch) Risperidone
Wikipedia Risperidone
Fluphenazine
long acting
Type Antipsychotic
Group Phenothiazines
links
Medscape Fluphenazine
PubChem 3372
PubMed Fluphenazine
Kompas (Dutch) Fluphenazine
Wikipedia Fluphenazine

Switch medication from Risperidone_LA to Fluphenazine_LA.[1] [2]

Nietinrijdenbord.png Stop Risperidone_LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Fluphenazine_LA
  • Day 28: Start depot according general dosing advice.
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[3]
    StopDepotStartArip.jpg
Nietinrijdenbord.png — Risperidone_LA
Eenrichtingbord.png — Fluphenazine_LA


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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