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Sertraline-agomelatine

Sertraline
Type Antidepressant
Group SSRI
links
Medscape Sertraline
PubChem 68617
PubMed Sertraline
Kompas (Dutch) Sertraline
Wikipedia Sertraline
Agomelatine
Type Antidepressant
Group other
links
ATC-code N06AX22
EMEA valdoxan
PubChem 82148
PubMed Agomelatine
Kompas (Dutch) Agomelatine
Wikipedia Agomelatine

Switch medication from sertraline to agomelatine.

Nietinrijdenbord.png Stop sertraline
  • Before day 1: Gradually reduce dosage of sertraline to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
  • Day 1: Reduce dosage of sertraline to a dosage of 25 mg/ day
  • Day 8: Stop administration of sertraline
Eenrichtingbord.png Start agomelatine
  • Day 9: start agomelatine in a dosage of 25 mg/day.
  • Day 16: if necessary, gradually increase dosage of agomelatine to target dose.[1]
Infobord.png More information
  • The reduction of the SSRI doses in 7-14 days could cause emotional instability, headache and flu-like symptoms. One could extend this period.
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