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Tranylcypromine-mianserine

Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Wikipedia Tranylcypromine
Mianserine
Type Antidepressant
Group other
links
PubChem 4184
PubMed Mianserine
Kompas (Dutch) Mianserine
Wikipedia Mianserine

Switch medication from tranylcypromine to mianserine.

Nietinrijdenbord.png Stop tranylcypromine
  • Gradually decrease the dosage of tranylcypromine with 10-20 mg/week.
  • When a dosage of 10 mg/day is reached, stop administration.
Eenrichtingbord.png Start mianserine
  • Day 1-14: a wash-out period of two weeks is necessary.
  • Day 15: start mianserine after this period in a low dosage of 30 mg/day.
Infobord.png More information
  • Occurrence of the serotonin syndrome is possible without a wash-out period.
  • The wash-out period is necessary for the MAO enzymes to restore their function.
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