Difference between revisions of "Valproic acid"

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{{Drug
 
{{Drug
| name = valproic acid
+
| name = Valproic acid
 
| group = anticonvulsant
 
| group = anticonvulsant
| otheruse = Mood stabilizer
+
| type = moodstabilizer
| type = Moodstabilizer
 
 
| wikipedia = valproic_acid
 
| wikipedia = valproic_acid
 
| medscape = 8885
 
| medscape = 8885
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| ftk = valproinezuur
 
| ftk = valproinezuur
 
| ATC = N03AG01
 
| ATC = N03AG01
| metabolization =  
+
| metabolization = * Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases.
* Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases.<ref name="ftk">{{FTK|valproinezuur}}</ref>
+
| metabolization_ref = <ref name="ftk">{{FTK|valproinezuur}}</ref>
 
| administration = O,R
 
| administration = O,R
 
| ctox = 150000
 
| ctox = 150000

Latest revision as of 00:19, 27 April 2010

Valproic acid
Type moodstabilizer
Group anticonvulsant
links
ATC-code N03AG01
PubChem 3121
PubMed acid%22 Valproic acid
Drugs.com valproic-acid
Kompas (Dutch) Valproic acid
Wikipedia Valproic acid

"-100000" can not be assigned to a declared number type with value 50000.


"-15" can not be assigned to a declared number type with value 10.










Valproic acid is a moodstabilizer in the group anticonvulsant.


Metabolization
  • Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases.[2]


  1. Farmacotherapeutisch Kompas; Toxicologie (dutch)
  2. 2.0 2.1 Farmacotherapeutisch Kompas - valproinezuur (dutch)
  3. KNMP; Informatorium Medicamentorum 2023; Monografie "valproaat" (Dutch)