Difference between revisions of "Venlafaxine-agomelatine"

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| to = agomelatine  
 
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* '''Day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.
 +
* '''Day 1:''' reduce a dosage of 75 mg/day to 37,5 mg/day.
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| start =  
 
| start =  
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* '''Day 1:''' simultaneously start administration of amitriptyline in a low dosage of 25 mg/day.
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* '''Day 8:''' stop administration of venlafaxine and continue administration of amitriptyline in a dosage of 50 mg/day.
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| info =  
 
| info =  
* }}
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* “Start low, go slow” for amitriptyline, and caution with this switch is necessary.
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* Venlafaxine is a weak inhibitor of CYP2D6, which metabolizes amitriptyline.}}

Revision as of 15:24, 26 May 2009

Venlafaxine
Type Antidepressant
Group SNRI
links
Medscape Venlafaxine
PubChem 5656
PubMed Venlafaxine
Kompas (Dutch) Venlafaxine
Wikipedia Venlafaxine
Agomelatine
Type Antidepressant
Group other
links
ATC-code N06AX22
EMEA valdoxan
PubChem 82148
PubMed Agomelatine
Kompas (Dutch) Agomelatine
Wikipedia Agomelatine

Switch medication from venlafaxine to agomelatine.

Nietinrijdenbord.png Stop venlafaxine
  • Day 0: gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.
  • Day 1: reduce a dosage of 75 mg/day to 37,5 mg/day.
Eenrichtingbord.png Start agomelatine
  • Day 1: simultaneously start administration of amitriptyline in a low dosage of 25 mg/day.
  • Day 8: stop administration of venlafaxine and continue administration of amitriptyline in a dosage of 50 mg/day.
Infobord.png More information
  • “Start low, go slow” for amitriptyline, and caution with this switch is necessary.
  • Venlafaxine is a weak inhibitor of CYP2D6, which metabolizes amitriptyline.
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