Difference between revisions of "Venlafaxine-agomelatine"

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| to = agomelatine  
 
| to = agomelatine  
 
| stop =  
 
| stop =  
* '''Day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.
+
{{downVenla}}
* '''Day 1:''' reduce to a dosage of 75 mg/day to 37,5 mg/day.
 
* '''Day 8:''' stop administration of venlafaxine
 
  
 
| start =  
 
| start =  
 
* '''Day 1:''' simultaneously start administration of agomelatine in a dosage of 25 mg/day.  
 
* '''Day 1:''' simultaneously start administration of agomelatine in a dosage of 25 mg/day.  
 
* '''Day 8:''' only continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day.}}
 
* '''Day 8:''' only continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day.}}

Revision as of 14:57, 17 July 2009

Venlafaxine
Type Antidepressant
Group SNRI
links
Medscape Venlafaxine
PubChem 5656
PubMed Venlafaxine
Kompas (Dutch) Venlafaxine
Wikipedia Venlafaxine
Agomelatine
Type Antidepressant
Group other
links
ATC-code N06AX22
EMEA valdoxan
PubChem 82148
PubMed Agomelatine
Kompas (Dutch) Agomelatine
Wikipedia Agomelatine

Switch medication from venlafaxine to agomelatine.[1] [2]

Nietinrijdenbord.png Stop venlafaxine
  • Day 1-14: gradually reduce dosage of venlafaxine to a maximum of 37,5 mg or 75 mg (slow release)/ day.
  • Day 15: stop administration of venlafaxine
Eenrichtingbord.png Start agomelatine
  • Day 1: simultaneously start administration of agomelatine in a dosage of 25 mg/day.
  • Day 8: only continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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