Zuclopenthixol LA-Sulpiride

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Zuclopenthixol
long acting
Type Antipsychotic
Group Thioxanthenes
links
PubChem 5311507
PubMed Zuclopenthixol
Kompas (Dutch) Zuclopenthixol
Wikipedia Zuclopenthixol
Sulpiride
Type Antipsychotic
Group Atypical AP
links
PubChem 5355
PubMed Sulpiride
Kompas (Dutch) Sulpiride
Wikipedia Sulpiride

Switch medication from Zuclopenthixol_LA to Sulpiride.[1] [2]

Nietinrijdenbord.png Stop Zuclopenthixol_LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Sulpiride
  • Week 1-3: approx. 25% of target dose
  • Week 4-6: approx. 50% of target dose
  • Week 7-9: approx. 75% of target dose
  • Week 10: target dose
Letopbord.png Cave
  • During this switch ECG monitoring is required because of possible QT-interval prolongation[3][4]
Infobord.png More information
Empty.jpg
Nietinrijdenbord.png — Zuclopenthixol_LA
Eenrichtingbord.png — Sulpiride


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. SPC Sertindole (Dutch)
  4. SPC Sertindole
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