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Type Antidepressant
Group other
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion
Type Antidepressant
Group other
PubChem 4184
PubMed Mianserine
Kompas (Dutch) Mianserine
Wikipedia Mianserine

Switch medication from bupropion to mianserine.

Nietinrijdenbord.png Stop bupropion
  • Gradually reduce dosage of bupropion to a maximum of 150 mg/day.
  • When a dosage of 150 mg/day is reached, stop administration.
Eenrichtingbord.png Start mianserine
  • A wash-out period of one week is recommended.
  • Start mianserine after this wash-out period in a normal dosage of 30-40 mg/day.
Infobord.png More information
  • Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.
  • Bupropion slows the metabolism of mianserine by CYP2D6.
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