Combining-Gabapentin-Olanzapine

From Psychiatrienet
Jump to: navigation, search
Gabapentin
Type moodstabilizer
Group anticonvulsant
links
ATC-code N03AX12
PubChem 3446
PubMed Gabapentin
Drugs.com gabapentin
Kompas (Dutch) Gabapentin
Wikipedia Gabapentin
Olanzapine
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AH03
Medscape Olanzapine
EMEA zyprexa
PubChem 4585
PubMed Olanzapine
Drugs.com olanzapine
Kompas (Dutch) Olanzapine
Wikipedia Olanzapine

Adding olanzapine to gabapentin.

Infobord.png General information
  
Gabapentin
  • Gabapentin is eliminated unchanged by the kidney for 100%.
  
Olanzapine
  • Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
  
Gabapentin
  
Olanzapine
  • This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects. [5]
Eenrichtingbord.png Start olanzapine
  
Olanzapine
  • Start olanzapine according to the general dosing advice.
Nietinrijdenbord.png Stop olanzapine
  
Olanzapine
Letopbord.png Cave
  • Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. [6]


  1. Farmacotherapeutisch Kompas - gabapentine (dutch)
  2. 2.0 2.1 2.2 2.3 KNMP; Informatorium Medicamentorum 2015; Monografie "olanzapine" (Dutch)
  3. Farmacotherapeutisch Kompas; Toxicologie (dutch)
  4. Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics; J Clin Psychiatry 2003;64:663-667
  5. Freeman et al. Mood stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry 1998;155:12-21
  6. Interactions between olanzapine and gabapentin on drugs.com
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.