Combining-Gabapentin-Topiramate

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Gabapentin
Type moodstabilizer
Group anticonvulsant
links
ATC-code N03AX12
PubChem 3446
PubMed Gabapentin
Drugs.com gabapentin
Kompas (Dutch) Gabapentin
Wikipedia Gabapentin
Topiramate
Type moodstabilizer
Group anticonvulsant
links
ATC-code N03AX11
PubChem 5284627
PubMed Topiramate
Drugs.com topiramate
Kompas (Dutch) Topiramate
Wikipedia Topiramate

Adding topiramate to gabapentin.

Infobord.png General information
  
Gabapentin
  • Gabapentin is eliminated unchanged by the kidney for 100%.
  
Topiramate
  • Topiramate induces CYP3A4 and is an inhibitor of CYP2C19.
  
Gabapentin
  
Topiramate
  • This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects. [2]
Eenrichtingbord.png Start topiramate
  
Topiramate
  • Start topiramate according to the general dosing advice.
Nietinrijdenbord.png Stop topiramate
  
Topiramate



  1. 1.0 1.1 1.2 Farmacotherapeutisch Kompas - gabapentine (dutch) Cite error: Invalid <ref> tag; name "ftk" defined multiple times with different content Cite error: Invalid <ref> tag; name "ftk" defined multiple times with different content
  2. Freeman et al. Mood stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry 1998;155:12-21
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