Fluoxetine-tranylcypromine

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Fluoxetine
Type Antidepressant
Group SSRI
links
Medscape Fluoxetine
PubChem 3386
PubMed Fluoxetine
Kompas (Dutch) Fluoxetine
Wikipedia Fluoxetine
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from fluoxetine to tranylcypromine.

Nietinrijdenbord.png Stop fluoxetine
  • Before day 1: reduce dosage of fluoxetine with about 20 mg per week.
  • Day 1: when a dosage of 20 mg/day is reached, stop fluoxetine.
Eenrichtingbord.png Start tranylcypromine
  • Day 1-35: a wash-out period of five weeks is necessary because of the long half live.
  • Day 36: start tranylcypromine in a low dosage of 20 mg/day for one week.
  • Day 43: after this week gradually increase the dosage of tranylcypromine.
Letopbord.png Cave
Infobord.png More information
  • Desmethylfluoxetine has a half live of about one week so a long wash-out period is necessary.
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