Flupenthixol LA-Fluphenazine LA

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Flupenthixol
long acting
Type Antipsychotic
Group Thioxanthenes
links
Medscape Flupenthixol
PubChem 17012
PubMed Flupenthixol
Kompas (Dutch) Flupenthixol
Wikipedia Flupenthixol
Fluphenazine
long acting
Type Antipsychotic
Group Phenothiazines
links
Medscape Fluphenazine
PubChem 3372
PubMed Fluphenazine
Kompas (Dutch) Fluphenazine
Wikipedia Fluphenazine

Switch medication from Flupenthixol_LA to Fluphenazine_LA.[1] [2]

Nietinrijdenbord.png Stop Flupenthixol_LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Fluphenazine_LA
  • Start depot according to general dosing advice on the day you normally would have injected the former depot.
  • Testing for acceptance and possible allergic reactions in a low dose can be carried out earlier.
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[3]
    StopDepotStartArip.jpg
Nietinrijdenbord.png — Flupenthixol_LA
Eenrichtingbord.png — Fluphenazine_LA


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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