Mianserine-maprotiline

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Mianserine
Type Antidepressant
Group other
links
PubChem 4184
PubMed Mianserine
Kompas (Dutch) Mianserine
Wikipedia Mianserine
Maprotiline
Type Antidepressant
Group NRI
links
Medscape Maprotiline
PubChem 4011
PubMed Maprotiline
Kompas (Dutch) Maprotiline
Wikipedia Maprotiline

Switch medication from mianserine to maprotiline.

Nietinrijdenbord.png Stop mianserine
  • Before day 1: gradually reduce dosage of mianserine to a maximum of 60 mg/ day.
  • Day 1: reduce a dosage of 60 mg/day to 30 mg/day.
Eenrichtingbord.png Start maprotiline

No wash-out period is needed.

  • Day 1: simultaneously start administration of maprotiline in a dosage of 25 mg/day.
  • Day 8: stop administration of mianserine and continue administration of maprotiline only in a dosage of 50 mg/day. If necessary, increase dosage of maprotiline.
  • Start low, go slow.


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