Switch medication from Sertindole to Zuclopenthixol_LA.
- Week 1-3: approx. 75% of initial dose
- Week 4-6: approx. 50% of initial dose
- Week 7-9: approx. 25% of initial dose
- Week 10: stop
- Day 1: Start depot according general dosing advice (Dotted line in graph)
- During this switch ECG monitoring is required because of possible QT-interval prolongation
- Alternatively, first switch to oral form and then switch to depot to manage possible (adverse) reactions. With a direct switch to a depot it is advisable to administer a low testdose in order to exclude adverse reactions.
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