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* Agomelatonine can be stopped abruptly for every dosage.
| start =
* No A wash-out period is not necessary.
* '''Day 1:''' start administration of doxepin the next day in a dosage of 25 mg/day.
* '''Day 2:''' increase dosage of doxepin to 50 mg/day.
* If necessary, increase dosage of doxepin with 25 mg every 2-3 days. }}