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* '''Day 3:''' reduce dosage of maprotiline to 25 mg/day.
| start =
* '''Day 13:''' simultaneously start administration of paroxetine in a normal dosage of 20 mg/day.
* '''Day 8:''' stop administration of maprotiline and continue administration of paroxetine.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Paroxetine is a strong inhibitor of CYP2D6, which metabolizes maprotiline. }}
