no edit summary
* '''Day 1:''' reduce dosage of clomipramine to 25 mg/day.
* '''Day 3:''' reduce dosage of clomipramine to 10 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of citalopram
/escitalopram in a normal dosage of 20 mg/day , resp. 10 mg/day. * '''Day 8:''' stop administration of clomipramine and continue administration of citalopram/escitalopram.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
/escitalopram are very weak inhibitors of CYP2D6, which metabolizes clomipramine.