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Clomipramine-citalopram

97 bytes removed, 23:51, 4 March 2010
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* '''Day 1:''' reduce dosage of clomipramine to 25 mg/day.
* '''Day 3:''' reduce dosage of clomipramine to 10 mg/day.
* '''Day 8:''' stop administration of clomipramine.
| start =
* '''Day 1:''' simultaneously start administration of citalopram/escitalopram in a normal dosage of 20 mg/day, resp. 10 mg/day.* '''Day 8:''' stop administration of clomipramine and continue administration of citalopram/escitalopram.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Citalopram/escitalopram are is a very weak inhibitors of CYP2D6, which metabolizes clomipramine.
}}
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