838
edits
Changes
Created page with '{{Drugswitch | from = fluvoxamine | to = clomipramine | stop = * '''Day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day when this dosage is > 50 mg/da...'
{{Drugswitch
| from = fluvoxamine
| to = clomipramine
| stop =
* '''Day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of fluvoxamine to a maximum of 25 mg/day.
| start =
Caution is necessary.
* '''Day 1:''' simultaneously start administration of clomipramine in a low dosage of 25-50 mg/day.
* '''Day 8:''' stop administration of fluvoxamine and continue administration of clomipramine in a dosage of 50-75 mg/day.
* Start low, go slow!
| info =
* Fluvoxamine slows the metabolism of clomipramine via CYP1A2 and CYP2D6.}}
| from = fluvoxamine
| to = clomipramine
| stop =
* '''Day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day when this dosage is > 50 mg/day.
* '''Day 1:''' reduce dosage of fluvoxamine to a maximum of 25 mg/day.
| start =
Caution is necessary.
* '''Day 1:''' simultaneously start administration of clomipramine in a low dosage of 25-50 mg/day.
* '''Day 8:''' stop administration of fluvoxamine and continue administration of clomipramine in a dosage of 50-75 mg/day.
* Start low, go slow!
| info =
* Fluvoxamine slows the metabolism of clomipramine via CYP1A2 and CYP2D6.}}
