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209 bytes removed, 14:49, 21 April 2010
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| add = topiramate
| info =
* Carbamazepine is principally metabolized by CYP3A4 (also CYP2C8), but is also a potent inducer of CYP1A2, CYP3A4 and UDP-glucuronosyltransferases.
* Topiramate induces CYP3A4 and is an inhibiter of CYP2C19.
| start =
* Carbamazepine can increase topiramate clearance. By adding topiramate to carbamazepine no dose adaptation is necessary. <ref name=”bazire”> Bazire S, Pshychotropic Drug Directory 2007, HealthComm UK Limited, Aberdeen, 2007. </ref> <ref name=”medicatiebewaking”> Schalekamp T. et al, Interacties met Psychofarmaca, Stichting Health Base, Houten, 2002. </ref>

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