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Combining-Ziprasidone-Topiramate

704 bytes added, 14:39, 15 June 2010
Created page with '{{Drugcombi | base = ziprasidone | add = topiramate | info = * Ziprasidone is metabolized by CYP3A4 and CYP1A2 (minor). * Dose adaptation will be recommended for this combinatio...'
{{Drugcombi
| base = ziprasidone
| add = topiramate
| info =
* Ziprasidone is metabolized by CYP3A4 and CYP1A2 (minor).
* Dose adaptation will be recommended for this combination.
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects.

| start =
* Start topiramate according general dosing advice.
| cave =
* Caution is advised when topiramate is prescribed with other drugs that predispose patients to heat-related disorders, including carbonic anhydrase inhibitors and drugs with anticholinergic activity. <ref name="drugscom">
{{Drugscominteract|ziprasidone-with-topiramate-2330-0-2216-0|ziprasidone|topiramate}}</ref>
}}
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