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Bupropion-amitriptyline

587 bytes added, 13:02, 4 May 2009
Created page with '{{Drugswitch | from = bupropion | to = amitriptyline | stop = * Gradually reduce dosage of bupropion to a maximum of 150 mg/ day. * When a dosage of 150 mg/day is reached, s...'
{{Drugswitch
| from = bupropion
| to = amitriptyline
| stop =
* Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.
* When a dosage of 150 mg/day is reached, stop administration.
| start =
* '''Day 1-3:''' start administration of amitriptyline in a low dosage of 25 mg/day.
* '''Day 4:''' increase dosage of amitriptyline to 50 mg/day and continue slowly increasing the dosage depending on the condition of the patient.
| info =
* Bupropion slows the metabolism of amitriptyline by CYP2D6.
* Caution is necessary at the start of administration of amitriptyline. }}
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