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Amitriptyline-fluoxetine

201 bytes removed, 13:50, 2 November 2015
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| to = fluoxetine
| stop =
* '''Before day 1:''' gradually reduce dosage of amitriptyline to a maximum of 50 mg/day.* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.* '''Day 8:''' stop dosage of amitriptyline.{{stopAmitriptyline1}}
| start =
* '''Day 8:''' start administration of fluoxetine in a normal dosage of 20 mg/day.
* '''Day 15:''' if necessary, increase dosage of fluoxetine.
| info =
{{SerotoninSyndromePossibletheorSS}}
* Fluoxetine and norfluoxetine are inhibitors of CYP2D6 (strong) and CYP3A4 (moderate), which metabolize amitriptyline.
{{review}}
}}
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