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Maprotiline-sertraline

239 bytes removed, 14:54, 2 November 2015
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* '''Before day 1:''' gradually reduce dosage of maprotiline to a maximum of 75 mg/day.* '''Day 1:''' reduce dosage of maprotiline to 50 mg/day.* '''Day 7:''' reduce dosage of maprotiline to 25 mg/day.* '''Day 14:''' stop dosage of maprotiline.{{stopMaprotiline}}
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* '''Day 7:''' simultaneously start administration of sertraline in a normal dosage of 50 mg/day.
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* Sertraline is a weak inhibitor of CYP2D6, which metabolizes maprotiline.
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