Trazodone-maprotiline

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Trazodone
Type Antidepressant
Group other
links
Medscape Trazodone
PubChem 5533
PubMed Trazodone
Kompas (Dutch) Trazodone
Wikipedia Trazodone
Maprotiline
Type Antidepressant
Group NRI
links
Medscape Maprotiline
PubChem 4011
PubMed Maprotiline
Kompas (Dutch) Maprotiline
Wikipedia Maprotiline

Switch medication from trazodone to maprotiline.

Nietinrijdenbord.png Stop trazodone
  • Before day 1: gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day.
  • Day 1: reduce dosage of trazodone to 100 mg/day.
  • Day 3: reduce dosage of trazodone to 50 mg/day.
  • Day 8: stop administration of trazodone.
Eenrichtingbord.png Start maprotiline

No wash-out period is needed.

  • Day 1: simultaneously start administration of maprotiline in a dosage of 25 mg/day.
  • Day 8: stop administration of trazodone and continue administration of maprotiline in a dosage of 50 mg/day.
  • Start low, go slow.
Infobord.png More information
  • The content of trazodone in the tablet, for example 100 mg or 150 mg, determines which exact doses are given.
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