Venlafaxine-vortioxetine

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Venlafaxine
Type Antidepressant
Group SNRI
links
Medscape Venlafaxine
PubChem 5656
PubMed Venlafaxine
Kompas (Dutch) Venlafaxine
Wikipedia Venlafaxine
Vortioxetine
Type Antidepressant
Group SMS
links
Medscape Vortioxetine
PubChem 9966051
PubMed Vortioxetine
Kompas (Dutch) Vortioxetine
Wikipedia Vortioxetine

Switch medication from venlafaxine to vortioxetine.

Nietinrijdenbord.png Stop venlafaxine
  • Before day 1: gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.
  • Day 1: reduce a dosage of 75 mg/day to 37,5 mg/day or 75 mg slow release.
  • Day 8: stop administration of venlafaxine.
Eenrichtingbord.png Start vortioxetine
  • A wash-out period of 1 day is advisable.
  • Day 10: start administration of vortioxetine in a low dosage of 10 mg/day.
Infobord.png More information

Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.

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